Improving sarcoid management: an epidemiological and molecular approach

Status
Applicant(s)
Researcher(s)
Research award
Country
Methodology

In this multi-disciplinary project we aim to identify the risk factors for sarcoids and to identify specific ‘molecular signatures’ that will aid in the management and treatment of sarcoids in donkeys.

Aims

In this multi-disciplinary project we aim to identify the risk factors for sarcoids and to identify specific ‘molecular signatures’ that will aid in the management and treatment of sarcoids in donkeys.

Objectives
  1. Identify epidemiological factors associated with development of sarcoids by using and enhancing the available Donkey Sanctuary clinical database.
  2. Identify key risk factors associated with development of sarcoids by mapping animal contact, location and key movements.
  3. Use RNA transcriptome profiling and viral genotyping to differentiate sarcoid types and use this data to develop prognostic biomarkers of recurrent/non-recurrent sarcoids to aid in treatment management.